Treatment of Premature Ovarian Failure by Ultrasound Intra Ovarian Injection of Bee Venom
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چکیده
Introduction: Idiopathic premature ovarian failure is defined as cessation of menstruation before the expected age of menopause (40 years) without detectable cause. the definitive line of treatment is egg donation which is not accepted in many countries. Bee venom is a miracle it has a unique composition so the aim of this work is to use ultrasound guided intra ovarian injection of Bee venom as a new modality for treatment of idiopathic premature ovarian failure. Patient and Methods: A 30 years old woman married for 10 years diagnosed as idiopathic premature ovarian failure and primary infertility (FSH 120 iu /ml, LH 42 iu/ml, E2 3 ng/ml, progesterone < 0.00l ng, Antimullerian hormone (AMH) < 0.00001 Bee venom in the form of APIS – injeels Ampoule 0.2 ml was injected through trans vaginal ultrasound in both ovaries. Primary outcome is occurrence of menstruation and secondary outcome ovulation and pregnancy. Follow up monthly for hormonal level, growing follicles, menstruation, ovulation, and occurrence of pregnancy
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تاریخ انتشار 2017